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Antibiotic Resistant Typhoid originating in Asia is spreading worldwide

Antibiotic Resistant Typhoid originating in Asia is spreading worldwide

The research conducted by The Lancet Microbe

Treatment-resistant Typhoid originating predominately from South Asia is spreading to other countries. According to new research, the increasing global threat of infections cannot be controlled by antibiotics. Scientists sequenced the genomes from 3,489 cases of S. Typhi, the bacteria that causes typhoid fever and kills over 100,000 people annually between 2014 and 2019. Data from four high-burden nations -- India, Nepal, Bangladesh, and Pakistan -- were combined with an analysis of 4,169 similar samples from more than 70 countries over a 113-year period, making it the largest study of its kind.

The research conducted by The Lancet Microbe found that while resistance to first-line treatments declined across South Asia, global issues remained. The number of strains that were able to overpower macrolides and quinolides, two important antibiotics, increased sharply. Antibiotic resistance has killed more people than HIV or malaria in 2019. Deadly fungus outbreaks in India and rising infections in the US are other examples. Misuse of antibiotics in humans and animals is exacerbated by poor sanitation. Jason Andrews, an associate professor at Stanford University and the study's lead author, said," The findings are a real cause for concern." He emphasized that prevention measures should be put in place, particularly in high-risk nations. The study was funded by the Bill & Melinda Gates Foundation.


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